Endocrine Abstracts

Somatostatinomas are rare neuroendocrine tumors diagnosed at a rather young age (mean age at diagnosis from 40 to 60 years). Non-auto-immune diabetes may associate with somatostatinoma as a result of abnormal somatostatin secretion, which inhibits insulin release. Steatorrhea and cholelithiasis are two other classical symptoms of these tumors. Here we report a case of somatostatinoma discovered while exploring a recently diagnosed diabetes, whose clinical and biological featur...

A lot of chromomosomal abnormalities have been described of which some are very unusual. Mosaicism refers to a condition where chromosomal (abnormalities) altered structure or number of chromosomes are present in some but not all cells. Polyploidy is defined as a condition where cells contain more than two homologous sets of chromosome, due to fertilization abnormalities; tetraploidy rarely allows birth of a living child but accounts for 6% of spontaneaous abortion.<p clas...